Running it at more than background volume with the loudness on does put some stress on it. Not saying that is the only explanation, I think it's definitely worth checking the bias. And it's always possible that components are on their way out that tested OK before.
EDIT: I'm not sure how many db the bass is boosted when you turn on the loudness on this amp, but they are often in the 3-6 db range. Note that increasing output by 3 db requires a DOUBLING of power. Granted you're only boosting the extreme low and high ends of the spectrum, but boosting the power into the woofer by 2x or 4x can stress the amp. A lot of people listen to music with bass boosted these days, even though that is not how music is meant to be played. If the artist and recording engineer wanted the bass to be boosted to that level, it would be that way on the recording. JMHO.